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Understanding lung cancer

How the lungs work, what happens when cancer develops, how it is staged, and what you can do. Explore the 3D model, then read on.

Choose a stage to see how the cancer changes
Tip

Click a label on the model

Drag to rotate and scroll to zoom. Each glowing point explains a part of the lungs.

Simplified illustration for education, not to anatomical scale. Shown as if the person is facing you: their right lung is on your left.

The basics

What is lung cancer?

Lung cancer starts when cells in the lung begin to grow out of control, usually in the lining of the airways. Over time they can form a mass (a tumour), invade nearby tissue, and spread through the lymph system or the blood to other parts of the body.

~2.5M
new cases worldwide in 2022, the most common cancer
~1.8M
deaths in 2022, the leading cause of cancer death
~85%
of lung cancers are non-small cell lung cancer
Early
detection greatly improves the chance of successful treatment
Types

The two main kinds

Doctors group lung cancers by how the cells look under a microscope, because that changes how they behave and how they are treated.

About 85%

Non-small cell lung cancer (NSCLC)

The most common kind. It usually grows more slowly. Main subtypes:

  • Adenocarcinoma: the most common subtype, often in the outer parts of the lung. It is also the most common type in people who have never smoked.
  • Squamous cell carcinoma: usually in the central airways, strongly linked to smoking.
  • Large cell carcinoma: can appear anywhere in the lung and tends to grow quickly.
About 15%

Small cell lung cancer (SCLC)

Less common but more aggressive. It grows fast and often has already spread by the time it is found, so it is usually treated with chemotherapy, radiotherapy and immunotherapy rather than surgery. It is almost always linked to smoking.

Risk factors

What raises the risk?

Anyone can get lung cancer, including people who have never smoked. These factors make it more likely:

Symptoms

Signs to watch for

Early lung cancer often causes no symptoms at all, which is why it is often found late, or by chance on a scan done for another reason. When symptoms do appear, they can include:

These symptoms are much more often caused by other, less serious conditions, such as infections. Only a doctor can find the cause.

Lung nodules

A "spot on the lung" is usually not cancer

A lung nodule is a small, roundish spot, up to 3 cm across, seen on a chest scan. Nodules are very common, and the large majority are benign: scars from old infections, small inflamed areas, or harmless growths.

Doctors decide what to do from the nodule's size, shape, density and growth, together with your personal risk factors. Often the next step is simply a repeat scan after some months to check whether it has changed.

What radiologists look at, and what this AI learned

  • Size: larger nodules are more likely to be cancer.
  • Edges: spiky ("spiculated") or irregular edges are more suspicious than smooth, round ones.
  • Density: solid, part-solid or "ground-glass"; each carries a different level of concern.
  • Growth: a nodule that grows between scans is more worrying than one that stays the same for years.
  • Calcium: certain calcification patterns usually mean a harmless nodule.
Try the nodule analyser
Staging

How far has it spread?

The stage describes the tumour's size and how far it has spread. It is the most important factor in choosing treatment and in the outlook. Survival rates below are broad US averages for non-small cell lung cancer; every person's situation is different.

5-year relative survival from the American Cancer Society (SEER data), grouped as localised / regional / distant. Treatments are improving, so recent outcomes may be better than these figures.

Diagnosis & treatment

From a suspicious scan to a plan

Screening

Low-dose CT screening can find lung cancer early in people at high risk. In the US, yearly screening is recommended for adults aged 50–80 with a heavy smoking history (20 pack-years or more) who smoke now or quit within the past 15 years. Rules differ by country, so ask your doctor.

Diagnosis

A suspicious nodule may lead to further imaging (such as PET-CT) and a biopsy, where a small tissue sample is examined. Only a biopsy can confirm cancer. Tests on the tissue also look for gene changes that guide treatment.

Treatment

Depending on the type and stage: surgery, radiotherapy, chemotherapy, targeted therapy (for tumours with specific gene changes) and immunotherapy, often combined. A team of specialists plans it together with the patient.

Lowering your risk

  • Don't smoke, or stop. Quitting at any age lowers the risk, and help such as counselling and medicines makes it more likely to succeed.
  • Avoid second-hand smoke at home and at work.
  • Test your home for radon where it is common, and fix high levels.
  • Reduce smoke and fumes indoors: ventilate when cooking, especially with wood, coal or other solid fuels.
  • Follow workplace safety rules around asbestos, silica, diesel exhaust and other chemicals.
  • Ask about screening if you are at high risk.
Get help

When to see a doctor

No website or AI can check your health. If something worries you, see a doctor. It is always OK to ask.

Get emergency help now (e.g. 112 in India and Europe, 911 in the US) if you cough up more than a little blood, have severe difficulty breathing, or have sudden severe chest pain.

Book an appointment with your doctor if you have

  • A cough that lasts more than 3 weeks, or a long-standing cough that changes
  • Any blood in what you cough up
  • Breathlessness, chest pain or hoarseness that doesn't go away
  • Chest infections that keep coming back
  • Weight loss or tiredness you can't explain

If you've been told you have a lung nodule

  • Keep every follow-up scan appointment, even if you feel well.
  • Ask what size and type it is, and what the plan is.
  • Tell your doctor about smoking, workplace exposures and family history.
  • Bring earlier scans if you have them: comparing them shows growth.
  • Don't use AI tools, including this one, to decide whether to follow medical advice.
Sources for this page
  • World Health Organization / IARC, GLOBOCAN 2022: global cancer statistics.
  • American Cancer Society: Lung cancer survival rates, types, risk factors and symptoms.
  • US Preventive Services Task Force (2021): Lung cancer screening recommendation.
  • US National Cancer Institute: Non-small cell and small cell lung cancer treatment (PDQ).

General education only, written for a broad audience; it may not reflect the latest guidance in your country.